2,000+ metabolites. Independently validated.
The most comprehensive metabolomic characterization of medicinal mushroom extracts ever conducted. Dual-panel mass spectrometry. Published in full.
Identified
Features
Quantified
Pathways
How we measured it
February 2026. An independent metabolomic laboratory in Japan conducted a dual-panel analysis of AHARA's extracts.
What's inside, verified
75 compounds absolutely quantified. Exact concentrations, not estimates.
| Compound | Amount | Function |
|---|---|---|
| Succinic acid | 26.58 mg / serving | SUCNR1 anti-inflammatory receptor activation |
| Lactic acid | 16.32 mg | Metabolic signaling, pH regulation |
| Citric acid | 8.53 mg | Krebs cycle, cellular energy |
| Choline | 5.74 mg | Acetylcholine precursor, memory |
| GABA | Quantified | Primary calming neurotransmitter |
| Adenine | Quantified | Direct adenosine precursor, sleep |
| Hypoxanthine | 170× enriched | Second adenosine pathway |
| Oleamide | Detected | Endogenous sleep molecule |
| Cytidine | 173× enriched | Cholinergic precursor, cognition |
| GPC | 78× enriched | Crosses blood-brain barrier |
| Ergosterol | 44× enriched | Vitamin D2 precursor |
| Sphingolipids | 23× enriched | Myelin sheath, nerve insulation |
17 pathways mapped
Not a single-mechanism supplement.
GABAergic
Calming + sleep
Cholinergic
Memory + attention
Purine / Adenosine
Natural sleep pressure
Serotonergic
Mood regulation
Endocannabinoid
Sleep + pain
Neuroprotective
Neuron repair
Gut-Brain Axis
Microbiome signaling
Anti-Inflammatory
Cytokine signaling
Immunomodulatory
Immune cell signaling
Neurogenesis
NGF neuron growth
Myelination
Nerve insulation
Hepatoprotective
Liver support
Cardiovascular
Circulation
Metabolic
Krebs cycle
Antioxidant
Ergothioneine
Membrane
Phospholipid precursors
Stress Response
HPA axis
Three breakthroughs
Water-based. No solvents.
Proprietary process that recovered the ganoderic acids without ethanol or methanol, verified by mass spectrometry. The cell-wall fiber survives intact, and so do the heat-sensitive compounds alcohol destroys.
85% improvement. p<0.001.
30-day observational study using PSQI, the gold-standard validated sleep instrument. Sleep onset dropped from 65 to 22 minutes. Zero tolerance. Zero grogginess. 150-person RCT underway in 2026.
Sublingual nanofiber.
Bypasses first-pass liver metabolism. Validated by University of Maryland TEM imaging. Co-developed with Dr. Subhas Malghan, Ph.D. (UC Berkeley), co-author of the FDA's first nanotechnology guidance document.
Every claim. Third-party validated.
Metabolomics
Independent metabolomic laboratory, Japan
CE-MS + LC-MS dual-panel
Nanofiber Structure
University of Maryland
Transmission Electron Microscopy
Compound Purity
ANAB-accredited laboratories
HPLC + mass spectrometry
- AHARA (2026). Comprehensive Metabolomic Characterization. Validated by Independent metabolomic laboratory, Japan.
- AHARA (2026). 30-Day Observational Sleep Study. PSQI-validated. p<0.001.
- University of Maryland (2025). TEM Imaging, Nanofiber Structure Validation
2,000+ metabolites. 17 pathways. Every claim independently verified.
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