METABOLOMIC DATA
Metabolite Encyclopedia
Over 2,000 metabolites mapped in AHARA's Reishi and Lion's Mane extracts via dual-panel CE-MS and LC-MS mass spectrometry. The 486 with the clearest documented roles are profiled in depth below.
2,000+
Metabolites Mapped
486
Profiled in Depth
17
Metabolic Pathways
0
Higher in Reishi
0
Higher in Lion's Mane
Lipid & Membrane Metabolism
★ 10 key65 compounds▾
The healthy fats that build and protect every cell in your body.
| Compound | What It Does | Higher In | Category |
|---|---|---|---|
| ★2-Arachidonoylglycerol | An endocannabinoid the body makes from fats, part of its natural endocannabinoid signaling system. | Reishi | Lipid |
| ★Arachidonic acid | An omega-6 fatty acid that is a key part of cell membranes and a starting point for the body's signaling molecules. | Reishi | Lipid |
| ★Cholic acid | A bile acid that helps the body break down and absorb dietary fats and acts as a signal in the gut. | Reishi | Lipid |
| ★Ergocalciferol-1 / Ergosterol | A mushroom sterol, the natural building block the body and sunlight convert toward vitamin D, supporting membranes and bone health. | Reishi | Lipid |
| ★Lactosylceramide(d18:1 / 24:1) | A healthy fat that helps build cell walls and supports nerve health. | Lion's Mane | Lipid |
| ★Lanosterol | A natural sterol that is an early building block in the body's pathway for making cholesterol and steroid hormones. | Reishi | Lipid |
| ★Linoleic acid | An essential omega-6 fatty acid the body cannot make on its own, important for healthy skin and cell membranes. | Reishi | Lipid |
| ★Oleic acid | A heart-friendly omega-9 fatty acid, the main fat in olive oil, that supports flexible, healthy cell membranes. | Lion's Mane | Lipid |
| ★Palmitic acid | A common saturated fatty acid the body uses as a building block for membranes and as an energy store. | Reishi | Lipid |
| ★Stearic acid | A saturated fatty acid used as a structural building block in cell membranes and as stored energy. | Lion's Mane | Lipid |
| 1,2-Dipalmitoyl-glycero-3-phosphoethanolamine | A fatty building block that forms the structure of every cell wall and helps cells send signals. | Reishi | Lipid |
| 1,2-Dipalmitoyl-glycero-3-phosphoglycerol | A fatty building block that forms the structure of every cell wall and helps cells send signals. | Reishi | Lipid |
| 1-Myristoyl-glycero-3-phosphoethanolamine | A fatty building block that forms the structure of every cell wall and helps cells send signals. | Reishi | Lipid |
| 1-Palmitoyl-glycero-3-phosphoethanolamine | A fatty building block that forms the structure of every cell wall and helps cells send signals. | Reishi | Lipid |
| 12-Ketolithocholic acid | A bile acid that helps the body break down and absorb dietary fats and acts as a signal in the gut. | Reishi | Lipid |
| 19-Methylarachidic acid / Heneicosanoic acid | A long-chain fatty acid that contributes to the structure of cell membranes. | Lion's Mane | Lipid |
| 2-Phosphoglyceric acid | A step the body uses to turn sugar into usable cellular energy. | Reishi | Lipid |
| 3-Dehydrochenodeoxycholic acid | A bile acid that helps the body break down and absorb dietary fats and acts as a signal in the gut. | Reishi | Lipid |
| 3-Oxocholic acid | A bile acid that helps the body break down and absorb dietary fats and acts as a signal in the gut. | Reishi | Lipid |
| 3-Phosphoglyceric acid | A step the body uses to turn sugar into usable cellular energy. | Reishi | Lipid |
| 7-Ketolithocholic acid | A bile acid that helps the body break down and absorb dietary fats and acts as a signal in the gut. | Reishi | Lipid |
| 7α-Hydroxycholesterol-1 | A sterol derivative that helps build cell membranes and serves as a building block for hormone-like molecules. | Lion's Mane | Lipid |
| 7α-Hydroxycholesterol-2 | A sterol derivative that helps build cell membranes and serves as a building block for hormone-like molecules. | Lion's Mane | Lipid |
| Allocholic acid-1 / Hyocholic acid-1 | A bile acid that helps the body break down and absorb dietary fats and acts as a signal in the gut. | Lion's Mane | Lipid |
| Allocholic acid-2 / Hyocholic acid-2 | A bile acid that helps the body break down and absorb dietary fats and acts as a signal in the gut. | Reishi | Lipid |
| Arachidic acid | A long-chain saturated fatty acid that contributes to cell membrane structure. | Reishi | Lipid |
| Cholesterol sulfate | A sterol derivative that helps build cell membranes and serves as a building block for hormone-like molecules. | Reishi | Lipid |
| Cholic acid 7-sulfate-1 | A bile acid that helps the body break down and absorb dietary fats and acts as a signal in the gut. | Lion's Mane | Lipid |
| Cholic acid 7-sulfate-2 | A bile acid that helps the body break down and absorb dietary fats and acts as a signal in the gut. | Lion's Mane | Lipid |
| Ethyl arachidonate-1 | The ester form of arachidonic acid, a fatty acid involved in membrane structure and signaling. | Lion's Mane | Lipid |
| Ethyl arachidonate-2 | The ester form of arachidonic acid, a fatty acid involved in membrane structure and signaling. | Reishi | Lipid |
| Fatty acid(12:1)-1 | A naturally occurring fatty acid that the body uses to build cell membranes and carry signals. | Reishi | Lipid |
| Fatty acid(12:1)-2 | A naturally occurring fatty acid that the body uses to build cell membranes and carry signals. | Reishi | Lipid |
| Fatty acid(13:0)-1 | A naturally occurring fatty acid that the body uses to build cell membranes and carry signals. | Reishi | Lipid |
| Fatty acid(13:0)-2 | A naturally occurring fatty acid that the body uses to build cell membranes and carry signals. | Reishi | Lipid |
| Fatty acid(14:1)-1 | A naturally occurring fatty acid that the body uses to build cell membranes and carry signals. | Reishi | Lipid |
| Fatty acid(14:1)-2 | A naturally occurring fatty acid that the body uses to build cell membranes and carry signals. | Reishi | Lipid |
| Fatty acid(14:3) | A naturally occurring fatty acid that the body uses to build cell membranes and carry signals. | Reishi | Lipid |
| Fatty acid(15:1)-1 | A naturally occurring fatty acid that the body uses to build cell membranes and carry signals. | Lion's Mane | Lipid |
| Fatty acid(15:1)-2 | A naturally occurring fatty acid that the body uses to build cell membranes and carry signals. | Lion's Mane | Lipid |
| Fatty acid(16:2) | A naturally occurring fatty acid that the body uses to build cell membranes and carry signals. | Reishi | Lipid |
| Fatty acid(16:3) | A naturally occurring fatty acid that the body uses to build cell membranes and carry signals. | Reishi | Lipid |
| Fatty acid(17:2) | A naturally occurring fatty acid that the body uses to build cell membranes and carry signals. | Reishi | Lipid |
| Fatty acid(17:3) | A naturally occurring fatty acid that the body uses to build cell membranes and carry signals. | Reishi | Lipid |
| Fatty acid(19:0) | A naturally occurring fatty acid that the body uses to build cell membranes and carry signals. | Lion's Mane | Lipid |
| Fatty acid(19:2) | A naturally occurring fatty acid that the body uses to build cell membranes and carry signals. | Reishi | Lipid |
| Fatty acid(25:0) | A naturally occurring fatty acid that the body uses to build cell membranes and carry signals. | Lion's Mane | Lipid |
| Fatty acid(26:0) | A naturally occurring fatty acid that the body uses to build cell membranes and carry signals. | Lion's Mane | Lipid |
| Glycerophosphorylethanolamine | A fatty building block that forms the structure of every cell wall and helps cells send signals. | Lion's Mane | Lipid |
| Glycochenodeoxycholic acid | A bile acid that helps the body break down and absorb dietary fats and acts as a signal in the gut. | Reishi | Lipid |
| Glycohyodeoxycholic acid | A bile acid that helps the body break down and absorb dietary fats and acts as a signal in the gut. | Reishi | Lipid |
| Isochenodeoxycholic acid-2 | A bile acid that helps the body break down and absorb dietary fats and acts as a signal in the gut. | Lion's Mane | Lipid |
| Lithocholic acid | A bile acid that helps the body break down and absorb dietary fats and acts as a signal in the gut. | Lion's Mane | Lipid |
| Murideoxycholic acid / Isoursodeoxycholic acid-1 | A bile acid that helps the body break down and absorb dietary fats and acts as a signal in the gut. | Lion's Mane | Lipid |
| Myristoleic acid | An omega-5 fatty acid found in natural fats that contributes to cell membrane structure. | Reishi | Lipid |
| Palmitoleic acid | An omega-7 fatty acid studied for supporting healthy metabolism and cell membranes. | Reishi | Lipid |
| Ricinoleic acid-1 | An unsaturated fatty acid studied for its soothing and barrier-supporting properties. | Lion's Mane | Lipid |
| Ricinoleic acid-2 | An unsaturated fatty acid studied for its soothing and barrier-supporting properties. | Reishi | Lipid |
| Ricinoleic acid-3 | An unsaturated fatty acid studied for its soothing and barrier-supporting properties. | Reishi | Lipid |
| Taurochenodeoxycholic acid | A bile acid that helps the body break down and absorb dietary fats and acts as a signal in the gut. | Lion's Mane | Lipid |
| Taurocholic acid | A bile acid that helps the body break down and absorb dietary fats and acts as a signal in the gut. | Lion's Mane | Lipid |
| Taurocholic acid 3-sulfate | A bile acid that helps the body break down and absorb dietary fats and acts as a signal in the gut. | Reishi | Lipid |
| Taurolithocholic acid | A bile acid that helps the body break down and absorb dietary fats and acts as a signal in the gut. | Lion's Mane | Lipid |
| α-Muricholic acid-1 | A bile acid that helps the body break down and absorb dietary fats and acts as a signal in the gut. | Lion's Mane | Lipid |
| α-Muricholic acid-2 / β-Muricholic acid | A bile acid that helps the body break down and absorb dietary fats and acts as a signal in the gut. | Lion's Mane | Lipid |
Amino Acid Metabolism
★ 2 key65 compounds▾
The protein building blocks your body uses to grow, repair, and make brain messengers.
| Compound | What It Does | Higher In | Category |
|---|---|---|---|
| ★Asp | Aspartic acid, a non-essential amino acid that serves as a brain messenger and supports energy production in the cellular energy cycle. | Lion's Mane | Amino Acid |
| ★Delphinidin 3-glucoside | An anthocyanin pigment with potent antioxidant and anti-inflammatory neuroprotective effects. | Reishi | Amino Acid |
| 2-Hydroxyglutaric acid | An organic acid involved in how cells make energy and control which genes turn on. | Reishi | Amino Acid |
| 3-Hydroxy-3-methylglutaric acid | A step the body uses when breaking down protein and making cholesterol. | Reishi | Amino Acid |
| 6-Phosphogluconic acid | A pentose phosphate pathway step that generates NADPH for antioxidant defense and production. | Reishi | Amino Acid Lipid |
| Apigenin 7-glucoside-1 | A glycosylated flavonoid with anti-inflammatory and neuroprotective properties. | Lion's Mane | Amino Acid |
| Apigenin 7-glucoside-2 | A plant antioxidant that crosses the blood-brain barrier and helps balance the brain’s calming signals. | Lion's Mane | Amino Acid |
| Apigenin 8-glucoside-1 / Genistin-1 | A C-glycosyl flavonoid with antioxidant activity and potential anxiolytic effects. | Lion's Mane | Amino Acid |
| Apigenin 8-glucoside-2 / Genistin-2 | A plant antioxidant that exhibits anti-inflammatory and free radical scavenging activity. | Lion's Mane | Amino Acid |
| Arg-Glu | A dipeptide of arginine and glutamate involved in nitrogen metabolism and nitric oxide signaling. | Lion's Mane | Amino Acid |
| Aspartame | A dipeptide derivative (aspartate-phenylalanine) that occurs naturally in trace amounts during protein metabolism. | Reishi | Amino Acid |
| Chenodeoxycholic acid 3-β-D-glucuronide | A processed bile acid involved in cholesterol excretion and liver and gut signaling. | Reishi | Amino Acid Lipid |
| Estriol 16α-glucuronide | A processed estrogen metabolite involved in hormone detoxification and excretion. | Reishi | Amino Acid |
| Estrone 3-glucuronide-1 | A glucuronidated estrogen metabolite that reflects estrogen metabolism and detoxification capacity. | Reishi | Amino Acid |
| Estrone 3-glucuronide-2 | A processed form of estrogen involved in hormone balance and the liver’s clearance process. | Reishi | Amino Acid |
| Etiocholan-3α-ol-17-one glucuronide | A processed form the body makes to safely process and clear compounds, part of natural detoxification. | Reishi | Amino |
| Formononetin 7-glucoside | A plant polyphenol studied for its antioxidant activity. | Reishi | Amino |
| Galactosamine-2 / Glucosamine | An amino sugar the body uses to build connective tissue and cell-surface structures. | Lion's Mane | Amino |
| Galacturonic acid / Glucuronic acid | A sugar or sugar-acid the body uses as fuel and a building block for energy metabolism. | Lion's Mane | Amino |
| Glu | An amino acid building block the body uses to make proteins and support metabolism. | Reishi | Amino |
| Glu-Glu | A small peptide of amino acids the body uses as a building block and signal. | Lion's Mane | Amino |
| Glucaric acid | A sugar or sugar-acid the body uses as fuel and a building block for energy metabolism. | Lion's Mane | Amino |
| Gluconic acid | A sugar or sugar-acid the body uses as fuel and a building block for energy metabolism. | Lion's Mane | Amino |
| Glucosaminic acid | An amino sugar the body uses to build connective tissue and cell-surface structures. | Reishi | Amino |
| Glucose 1-phosphate | A sugar or sugar-acid the body uses as fuel and a building block for energy metabolism. | Reishi | Amino |
| Glucose 6-phosphate | A sugar or sugar-acid the body uses as fuel and a building block for energy metabolism. | Lion's Mane | Amino |
| Glucosylceramide(d18:1 / 24:1) | A healthy fat that helps build nerve cells and supports how they communicate. | Reishi | Amino |
| Gly-Asp | A small peptide of amino acids the body uses as a building block and signal. | Lion's Mane | Amino |
| H-Asp(Gly-OH)-OH | A small peptide of the amino acids aspartate and glycine that the body uses as a building block. | Reishi | Amino |
| His-Glu | A small peptide of amino acids the body uses as a building block and signal. | Lion's Mane | Amino |
| Lithocholic acid 3-O-glucuronide | A processed form the body makes to safely process and clear compounds, part of natural detoxification. | Lion's Mane | Amino |
| Luteolin 7-glucoside-1 | A plant polyphenol studied for its antioxidant activity. | Lion's Mane | Amino |
| Luteolin 7-glucoside-2 | A plant polyphenol studied for its antioxidant activity. | Reishi | Amino |
| Luteolin 7-glucoside-3 | A plant polyphenol studied for its antioxidant activity. | Lion's Mane | Amino |
| Monomethyl glutaric acid | An organic acid step in amino-acid and energy metabolism. | Reishi | Amino |
| N-Acetylasparagine | A stored form of the amino acid asparagine that the body draws on for protein building and metabolism. | Reishi | Amino |
| N-Acetylglucosamine 1-phosphate | An amino sugar the body uses to build connective tissue and cell-surface structures. | Reishi | Amino |
| N-Acetylglucosylamine | An amino sugar the body uses to build connective tissue and cell-surface structures. | Reishi | Amino |
| N-Acetylglutamine | A gentle, stable form of glutamine, an amino acid the gut and muscles use as fuel and a building block. | Lion's Mane | Amino |
| N5-Ethylglutamine | A natural relative of glutamine, an amino acid the body uses for gut repair and steady energy. | Reishi | Amino |
| Peonidin 3-glucoside | A plant polyphenol studied for its antioxidant activity. | Reishi | Amino |
| Pyroglutamine | A cyclized form of glutamine that has been studied for its role in memory and mental clarity. | Reishi | Amino |
| Ser-Glu | A small peptide of amino acids the body uses as a building block and signal. | Lion's Mane | Amino |
| Tectorigenin 7-O-xylosylglucoside | A plant polyphenol studied for its antioxidant activity. | Lion's Mane | Amino |
| Testosterone glucuronide-1 | A processed form of a steroid hormone involved in energy and body composition. | Lion's Mane | Amino |
| Testosterone glucuronide-2 | A processed form of a steroid hormone involved in energy and body composition. | Lion's Mane | Amino |
| Thr-Asp | A small peptide of amino acids the body uses as a building block and signal. | Lion's Mane | Amino |
| Tyr-Glu | A small peptide of amino acids the body uses as a building block and signal. | Lion's Mane | Amino |
| dTDP-glucose | A sugar or sugar-acid the body uses as fuel and a building block for energy metabolism. | Reishi | Amino |
| β-Asp-Leu | A small peptide of amino acids the body uses as a building block and signal. | Lion's Mane | Amino |
| β-Estradiol 17-glucuronide-1 | A processed form the body makes to safely process and clear compounds, part of natural detoxification. | Reishi | Amino |
| β-Estradiol 17-glucuronide-2 | A processed form the body makes to safely process and clear compounds, part of natural detoxification. | Reishi | Amino |
| γ-Glu-Ala | A small peptide involved in the body's antioxidant (glutathione) system. | Reishi | Amino |
| γ-Glu-Arg_divalent | A small peptide involved in the body's antioxidant (glutathione) system. | Lion's Mane | Amino |
| γ-Glu-Asn | A small peptide involved in the body's antioxidant (glutathione) system. | Reishi | Amino |
| γ-Glu-Gln | A small peptide involved in the body's antioxidant (glutathione) system. | Reishi | Amino |
| γ-Glu-Glu | A small peptide involved in the body's antioxidant (glutathione) system. | Reishi | Amino |
| γ-Glu-Ile / γ-Glu-Leu | A small peptide involved in the body's antioxidant (glutathione) system. | Reishi | Amino |
| γ-Glu-Ornitine-1 | A small peptide involved in the body's antioxidant (glutathione) system. | Reishi | Amino |
| γ-Glu-Ornitine-2 / H-Asp(Lys-OH)-OH | A small peptide involved in the body's antioxidant (glutathione) system. | Lion's Mane | Amino |
| γ-Glu-Phe | A small peptide involved in the body's antioxidant (glutathione) system. | Reishi | Amino |
| γ-Glu-Ser | A small peptide involved in the body's antioxidant (glutathione) system. | Lion's Mane | Amino |
| γ-Glu-Thr | A small peptide involved in the body's antioxidant (glutathione) system. | Reishi | Amino |
| γ-Glu-Tyr | A small peptide involved in the body's antioxidant (glutathione) system. | Reishi | Amino |
| γ-Glu-Val-Gly | A small peptide involved in the body's antioxidant (glutathione) system. | Lion's Mane | Amino |
Inflammation & Immune Response
37 compounds▾
The natural signals your body uses to manage inflammation and defend itself.
| Compound | What It Does | Higher In | Category |
|---|
| 11β-Prostaglandin F2α | An inflammation signal involved in inflammatory signaling and muscle tone. | Reishi | Inflammation |
| 12(S)-HETE | A hydroxyeicosatetraenoic acid involved in inflammation, platelet aggregation, and immune cell migration. | Reishi | Other |
| 12(S)-HPETE-1 | A fat-derived signal the body makes as part of its inflammation response. | Reishi | Other |
| 12(S)-HPETE-3 | A hydroperoxy fatty acid step in arachidonic acid metabolism and inflammatory signaling. | Reishi | Other |
| 13,14-Dihydro-15-keto-prostaglandin D2-2 | A breakdown product of an inflammation signal, associated with the winding-down of inflammation. | Reishi | Inflammation |
| 13,14-Dihydro-15-keto-prostaglandin E1-1 / 13,14-Dihydro-15-keto-prostaglandin F2α-1 | An inflammation signal breakdown product used as a sign of inflammation. | Reishi | Inflammation |
| 13,14-Dihydro-15-keto-prostaglandin E1-2 / 13,14-Dihydro-15-keto-prostaglandin F2α-2 | An inflammation signal metabolite indicating resolution of acute inflammatory responses. | Reishi | Inflammation |
| 13,14-Dihydro-15-keto-prostaglandin E1-3 / 13,14-Dihydro-15-keto-prostaglandin F2α-3 | An inflammation-related compound involved in the winding-down of inflammation. | Reishi | Inflammation |
| 13,14-Dihydro-15-keto-prostaglandin E2-3 / 13,14-Dihydro-15-keto-prostaglandin D2-1 | An inflammation signal breakdown product that serves as a sign of inflammation activity. | Lion's Mane | Inflammation |
| 13,14-Dihydro-19(R)-hydroxy-prostaglandin E1 | An inflammation-related compound involved in blood flow and inflammatory signaling. | Lion's Mane | Inflammation |
| 13,14-Dihydro-prostaglandin E1-1 | An inflammation-related compound involved in inflammatory signaling and blood flow. | Reishi | Inflammation |
| 13,14-Dihydro-prostaglandin E1-2 | An inflammation-related compound involved in muscle tone and inflammatory signaling. | Lion's Mane | Inflammation |
| 15(S)-HETE | A fat-derived signal involved in the immune response. | Reishi | Other |
| 15(S)-HPETE-2 / 12(S)-HPETE-2 | A hydroperoxy fatty acid that serves as a building block the body uses to make anti-inflammatory lipoxins. | Reishi | Other |
| 15-Deoxy-Δ12,14-prostaglandin D2-1 | A signaling lipid associated with the winding-down of inflammation. | Reishi | Inflammation |
| 15-Deoxy-Δ12,14-prostaglandin D2-2 | A signaling lipid the body uses to regulate its natural inflammation and immune response. | Lion's Mane | Inflammation |
| 15-Deoxy-Δ12,14-prostaglandin J2 | A signaling lipid the body uses to regulate its natural inflammation and immune response. | Reishi | Inflammation |
| 15-Keto-prostaglandin E2-1 | A signaling lipid the body uses to regulate its natural inflammation and immune response. | Lion's Mane | Inflammation |
| 15-Keto-prostaglandin E2-2 | A signaling lipid the body uses to regulate its natural inflammation and immune response. | Lion's Mane | Inflammation |
| 15-Methyl prostaglandin F2α | A signaling lipid the body uses to regulate its natural inflammation and immune response. | Lion's Mane | Inflammation |
| 5-HEPE / 15(S)-HPETE-1 | A signaling lipid the body uses to regulate its natural inflammation and immune response. | Reishi | Inflammation |
| 6-Keto-prostaglandin E1 | A signaling lipid the body uses to regulate its natural inflammation and immune response. | Lion's Mane | Inflammation |
| 6-Keto-prostaglandin F1α | A signaling lipid the body uses to regulate its natural inflammation and immune response. | Reishi | Inflammation |
| Fucoxanthin-1 | A natural carotenoid pigment studied for antioxidant and metabolic support. | Reishi | Inflammation |
| Fucoxanthin-2 | A natural carotenoid pigment studied for antioxidant and metabolic support. | Reishi | Inflammation |
| Leukotriene B4-1 | A signaling lipid the body uses to regulate its natural inflammation and immune response. | Reishi | Inflammation |
| Leukotriene B4-2 | A signaling lipid the body uses to regulate its natural inflammation and immune response. | Reishi | Inflammation |
| Prostaglandin A1 / Prostaglandin B1-1 | A signaling lipid the body uses to regulate its natural inflammation and immune response. | Reishi | Inflammation |
| Prostaglandin A2 / Prostaglandin J2 | A signaling lipid the body uses to regulate its natural inflammation and immune response. | Lion's Mane | Inflammation |
| Prostaglandin B1-2 | A signaling lipid the body uses to regulate its natural inflammation and immune response. | Reishi | Inflammation |
| Prostaglandin B3 / Prostaglandin A3 | A signaling lipid the body uses to regulate its natural inflammation and immune response. | Lion's Mane | Inflammation |
| Prostaglandin D3-1 | A signaling lipid the body uses to regulate its natural inflammation and immune response. | Lion's Mane | Inflammation |
| Prostaglandin D3-2 | A signaling lipid the body uses to regulate its natural inflammation and immune response. | Lion's Mane | Inflammation |
| Prostaglandin D3-3 | A signaling lipid the body uses to regulate its natural inflammation and immune response. | Reishi | Inflammation |
| Prostaglandin E2 | A signaling lipid the body uses to regulate its natural inflammation and immune response. | Lion's Mane | Inflammation |
| Prostaglandin F1α | A signaling lipid the body uses to regulate its natural inflammation and immune response. | Lion's Mane | Inflammation |
| Prostaglandin F2α | A signaling lipid the body uses to regulate its natural inflammation and immune response. | Reishi | Inflammation |
One-Carbon & Methylation
★ 1 key37 compounds▾
Compounds your body uses to control which genes turn on and to build brain messengers.
| Compound | What It Does | Higher In | Category |
|---|---|---|---|
| ★Betaine | A methyl donor that supports homocysteine metabolism, liver function, and cellular osmoregulation. | Reishi | Other |
| 1-Methyl-4-imidazoleacetic acid | A histamine metabolite produced by gene regulation, reflecting histamine turnover in the brain and periphery. | Reishi | Other |
| 2-Amino-2-methyl-1-propanol | An amino alcohol involved in lipid metabolism and used as a buffer in biochemical reactions. | Reishi | Other |
| 2-Methylserine | A methylated amino acid derivative involved in one-carbon metabolism and folate cycling. | Reishi | Other |
| 24-Methylenecycloartanol-1 | A plant sterol building block found in fungi that supports membrane integrity and steroid production. | Lion's Mane | Other |
| 24-Methylenecycloartanol-2 | A cycloartane-type triterpenoid involved in ergosterol production in mushrooms. | Lion's Mane | Other |
| 4-Methyl-2-oxovaleric acid / 3-Methyl-2-oxovaleric acid / 2-Oxohexanoic acid | A branched-chain keto acid from leucine breakdown, important for energy production during fasting. | Lion's Mane | Other |
| 4-Methyl-5-thiazoleethanol | A thiamine (vitamin B1) breakdown product involved in energy metabolism and nerve function. | Lion's Mane | Other |
| 4-Methylaminobutyric acid / 5-Aminovaleric acid | A compound related to GABA, involved in the brain's inhibitory (calming) signaling. | Reishi | Other |
| 4-Trimethylammoniobutanal | A carnitine production step essential for fatty acid transport into mitochondria. | Reishi | Other |
| 5,6-Dimethylbenzimidazole | The lower ligand of vitamin B12, essential for gene regulation reactions and red blood cell formation. | Reishi | Other |
| 5-Methylfuran-2-carboxylic acid | A furan derivative from carbohydrate metabolism with potential antioxidant properties. | Lion's Mane | Other |
| Betaine aldehyde_+H2O | A step the body uses to make betaine, which supports healthy gene activity. | Reishi | Other |
| Carboxymethyllysine | An advanced glycation end-product (AGE) marker linked to cell stress and aging processes. | Lion's Mane | Other |
| Crotonic acid betaine | A fat-carrier molecule the body uses to turn fat into energy in its cellular power plants. | Reishi | Other |
| Epigallocatechin 3-O-(3-O-methyl)gallate | A plant polyphenol studied for its antioxidant activity. | Lion's Mane | One-Carbon |
| Episesamin | A sesame-seed lignan studied for its antioxidant support and help with healthy fat metabolism. | Reishi | One-Carbon |
| Galactosamine-1 / Mannosamine | An amino sugar the body uses to build connective tissue and cell-surface structures. | Lion's Mane | One-Carbon |
| Gallocatechin 3-methylgallate | A plant polyphenol studied for its antioxidant activity. | Lion's Mane | One-Carbon |
| Hexanoic acid / 4-Methylpentanoic acid | A short or medium-chain fatty acid the body uses as fuel and a building block. | Reishi | One-Carbon |
| Methionine sulfoxide | A marker the body forms when it neutralizes cell stress, part of its natural antioxidant defense. | Lion's Mane | One-Carbon |
| Methyl sulfate | A methyl-donor or gene regulation product the body uses to regulate genes and balance brain messengers. | Reishi | One-Carbon |
| Methylguanidine | A methyl-donor or gene regulation product the body uses to regulate genes and balance brain messengers. | Lion's Mane | One-Carbon |
| N-Methylphenylethanolamine | A trace amine related to the body's natural mood and alertness messengers. | Reishi | One-Carbon |
| N-Methylproline | A methyl-donor or gene regulation product the body uses to regulate genes and balance brain messengers. | Reishi | One-Carbon |
| N-Methylputrescine / Cadaverine | A polyamine the body uses to support healthy cell growth and renewal. | Reishi | One-Carbon |
| N6,N6,N6-Trimethyllysine | A methyl-donor or gene regulation product the body uses to regulate genes and balance brain messengers. | Reishi | One-Carbon |
| N6,N6-Dimethyllysine | A methyl-donor or gene regulation product the body uses to regulate genes and balance brain messengers. | Reishi | One-Carbon |
| N6-Methyllysine | A methyl-donor or gene regulation product the body uses to regulate genes and balance brain messengers. | Reishi | One-Carbon |
| Nω-(Carboxymethyl)arginine | A methyl-donor or gene regulation product the body uses to regulate genes and balance brain messengers. | Reishi | One-Carbon |
| Nω-Methylarginine | A methyl-donor or gene regulation product the body uses to regulate genes and balance brain messengers. | Lion's Mane | One-Carbon |
| Pimelic acid / 3-Methyladipic acid | A short or medium-chain fatty acid the body uses as fuel and a building block. | Lion's Mane | One-Carbon |
| S-Carboxymethylcysteine | A methyl-donor or gene regulation product the body uses to regulate genes and balance brain messengers. | Reishi | One-Carbon |
| Sesamin-1 | A sesame-seed lignan studied for antioxidant support and balanced fat metabolism. | Lion's Mane | One-Carbon |
| Sesamin-2 | A sesame-seed lignan studied for antioxidant support and balanced fat metabolism. | Lion's Mane | One-Carbon |
| Trimethylamine | A methyl-donor or gene regulation product the body uses to regulate genes and balance brain messengers. | Reishi | One-Carbon |
| γ-Butyrobetaine | A nutrient the body uses as a precursor in carnitine synthesis and methyl-donor reactions. | Reishi | One-Carbon |
Neuroprotection & Brain Health
36 compounds▾
Compounds that protect your brain cells and support healthy brain structure.
| Compound | What It Does | Higher In | Category |
|---|
| 1-Deoxysphingosine-1 | An atypical fatty building block involved in healthy-fat processing and healthy nerve-cell walls. | Lion's Mane | Lipid |
| 1-Deoxysphingosine-2 | A healthy fat metabolite involved in healthy nerve function. | Reishi | Lipid |
| Acylcarnitine(10:0)-1 | A fat-carrier molecule that delivers fat into cells to be burned for brain energy. | Lion's Mane | Energy |
| Acylcarnitine(10:0)-2 | A medium-chain fatty acid carrier supporting burning fat for energy and backup energy production. | Lion's Mane | Energy |
| Acylcarnitine(12:0)-1 | A lauric acid carnitine processed form that supports fat burning for cellular energy. | Reishi | Energy |
| Acylcarnitine(12:0)-2 | A fat-carrier molecule involved in fat processing for energy and energy balance. | Reishi | Energy |
| Acylcarnitine(12:1) | A fat-carrier molecule that reflects the body actively burning fat for energy. | Reishi | Energy |
| Acylcarnitine(14:0)-1 | A fat-carrier molecule that delivers fat into cells to be burned for energy. | Lion's Mane | Energy |
| Acylcarnitine(14:0)-2 | A fat-carrier molecule supporting cell-energy fat burning and neuroprotection. | Reishi | Energy |
| Acylcarnitine(14:1)-1 | A fat-carrier molecule involved in turning fat into cellular energy. | Reishi | Energy |
| Acylcarnitine(14:1)-2 | A fat-carrier molecule supporting neuronal the cell's energy centers and lipid turnover. | Lion's Mane | Energy |
| Acylcarnitine(14:2)-1 | A fat-carrier molecule that reflects the body actively burning fat for energy. | Reishi | Energy |
| Acylcarnitine(14:2)-2 | A dienoyl-carnitine processed form involved in the degradation of unsaturated fatty acids. | Reishi | Energy |
| Acylcarnitine(14:2)-3 | A fat-carrier molecule the body uses while processing fats for energy. | Reishi | Energy |
| Acylcarnitine(14:3) | A trienoyl-carnitine reflecting the burning of fats for energy. | Reishi | Energy |
| Acylcarnitine(16:1)-1 | Carries fatty acids into mitochondria so cells can burn them for energy, supporting brain and muscle. | Reishi | Neuroprotection |
| Acylcarnitine(16:1)-2 | Carries fatty acids into mitochondria so cells can burn them for energy, supporting brain and muscle. | Reishi | Neuroprotection |
| Acylcarnitine(16:2) | Carries fatty acids into mitochondria so cells can burn them for energy, supporting brain and muscle. | Reishi | Neuroprotection |
| Acylcarnitine(17:0) | Carries fatty acids into mitochondria so cells can burn them for energy, supporting brain and muscle. | Lion's Mane | Neuroprotection |
| Acylcarnitine(18:0)-1 | Carries fatty acids into mitochondria so cells can burn them for energy, supporting brain and muscle. | Lion's Mane | Neuroprotection |
| Acylcarnitine(18:0)-2 | Carries fatty acids into mitochondria so cells can burn them for energy, supporting brain and muscle. | Reishi | Neuroprotection |
| Acylcarnitine(18:1) | Carries fatty acids into mitochondria so cells can burn them for energy, supporting brain and muscle. | Lion's Mane | Neuroprotection |
| Acylcarnitine(18:2)-1 | Carries fatty acids into mitochondria so cells can burn them for energy, supporting brain and muscle. | Reishi | Neuroprotection |
| Acylcarnitine(18:2)-2 | Carries fatty acids into mitochondria so cells can burn them for energy, supporting brain and muscle. | Reishi | Neuroprotection |
| Acylcarnitine(20:1) | Carries fatty acids into mitochondria so cells can burn them for energy, supporting brain and muscle. | Lion's Mane | Neuroprotection |
| Carnitine | Carries fatty acids into mitochondria so cells can burn them for energy, supporting brain and muscle. | Reishi | Neuroprotection |
| Linoleyl ethanolamide / N-Acetylsphingosine | A healthy fat that helps build nerve cells and supports how they communicate. | Reishi | Neuroprotection |
| Malonylcarnitine | Carries fatty acids into mitochondria so cells can burn them for energy, supporting brain and muscle. | Reishi | Neuroprotection |
| N-Acetylcarnosine | A form of carnosine, an antioxidant compound found in nerve and eye tissue. | Reishi | Neuroprotection |
| O-Acetylcarnitine | Carries fatty acids into mitochondria so cells can burn them for energy, supporting brain and muscle. | Reishi | Neuroprotection |
| Palmitoylcarnitine | Carries fatty acids into mitochondria so cells can burn them for energy, supporting brain and muscle. | Lion's Mane | Neuroprotection |
| Phytosphingosine | A healthy fat that helps build nerve cells and supports how they communicate. | Reishi | Neuroprotection |
| Sphingomyelin(d18:1 / 18:0) | A healthy fat that helps build nerve cells and supports how they communicate. | Lion's Mane | Neuroprotection |
| Sphingosine | A healthy fat that helps build nerve cells and supports how they communicate. | Reishi | Neuroprotection |
| Sphingosine 1-phosphate | A healthy fat that helps build nerve cells and supports how they communicate. | Lion's Mane | Neuroprotection |
| Sphingosine(d20:1) | A healthy fat that helps build nerve cells and supports how they communicate. | Reishi | Neuroprotection |
Sleep & Circadian Rhythm
★ 9 key29 compounds▾
The natural compounds that guide your sleep, wake cycles, and body clock.
| Compound | What It Does | Higher In | Category |
|---|---|---|---|
| ★3-Hydroxykynurenine | A tryptophan metabolite in the kynurenine pathway, studied in relation to oxidative balance in the brain. | Reishi | Neuroprotective |
| ★6-Hydroxymelatonin | The form the liver makes from melatonin, reflecting melatonin production and circadian rhythm status. | Reishi | Sleep |
| ★Adenosine | A natural compound that builds up while you're awake and signals the brain that it's time for sleep. | Lion's Mane | Sleep |
| ★Cinnamoylglycine | A gut-derived phenolic glycine processed form that reflects microbial metabolism and phase II detoxification. | Reishi | Sleep |
| ★GABA | Gamma-aminobutyric acid, the brain's main inhibitory (calming) neurotransmitter, central to the transition into sleep. | Lion's Mane | Sleep |
| ★Kynurenic acid-1 | A neuroprotective tryptophan metabolite that blocks excitotoxic the brain’s overactive signals. | Reishi | Neuroprotective |
| ★Kynurenic acid-2 | A natural brain compound with a calming effect on brain signals and anti-seizure potential. | Reishi | Neuroprotective |
| ★Kynurenine | A compound the body makes from tryptophan, involved in immune signaling and the kynurenine pathway. | Lion's Mane | Neuroprotective |
| ★Oleamide | A fatty acid amide that accumulates in the brain during wakefulness and is associated with the onset of sleep through the GABA and serotonin systems. | Reishi | Sleep |
| 1-Methylhydantoin / Glycine anhydride | A creatinine-related metabolite involved in nitrogen metabolism and circadian waste clearance. | Reishi | Sleep |
| 2'-Deoxyadenosine / 5'-Deoxyadenosine | A DNA building block that serves as an a compound related to the sleep signal adenosine involved in recycling and sleep signaling. | Lion's Mane | Sleep |
| 2-Quinolinecarboxylic acid | A step the body makes while breaking down the amino acid tryptophan. | Lion's Mane | Other |
| 3-Methylcrotonylglycine-1 | A leucine breakdown byproduct processed with glycine for detoxification and excretion. | Reishi | Sleep |
| 3-Methylcrotonylglycine-2 | An compound from protein breakdown and the cell's energy centers. | Reishi | Sleep |
| 4,6-Dihydroxyquinoline | A quinoline derivative from tryptophan degradation with potential neuromodulatory activity. | Reishi | Other |
| 4-Hydroxyquinoline | A tryptophan breakdown product with antimicrobial properties that helps balance gut-brain signaling. | Reishi | Other |
| N,N-Dimethylglycine | A methyl-donor or gene regulation product the body uses to regulate genes and balance brain messengers. | Reishi | Sleep |
| N-(o-Toluoyl)glycine-1 / Phenaceturic acid-1 | A glycine-linked compound formed as the body processes and clears other molecules. | Lion's Mane | Sleep |
| N-(o-Toluoyl)glycine-2 / Phenaceturic acid-2 | A glycine-linked compound formed as the body processes and clears other molecules. | Lion's Mane | Sleep |
| N-Acetylglycine | A glycine-linked compound formed as the body processes and clears other molecules. | Reishi | Sleep |
| N-Acetyltaurine-1 | A form of taurine, a calming amino acid the body links to relaxation and restful sleep. | Reishi | Sleep |
| N-Acetyltaurine-2 | A form of taurine, a calming amino acid the body links to relaxation and restful sleep. | Reishi | Sleep |
| N-Acetyltryptophan | A form of tryptophan, the amino acid the body converts along the path to serotonin and melatonin for sleep. | Reishi | Sleep |
| N-Hexanoylglycine | A glycine-linked compound formed as the body processes and clears other molecules. | Lion's Mane | Sleep |
| N6-Methyladenosine | A natural sleep-pressure molecule that builds up while you are awake and helps signal the body toward sleep. | Lion's Mane | Sleep |
| Oleamide-1 | A natural fatty acid the body links to drowsiness and the onset of restful sleep. | Reishi | Sleep |
| Oleamide-2 | A natural fatty acid the body links to drowsiness and the onset of restful sleep. | Reishi | Sleep |
| Quinolinic acid | A compound in the tryptophan (kynurenine) pathway, studied in relation to mood and sleep signaling. | Lion's Mane | Sleep |
| Succinyladenosine | A natural sleep-pressure molecule that builds up while you are awake and helps signal the body toward sleep. | Reishi | Sleep |
Neurotransmitter Synthesis
★ 4 key32 compounds▾
The raw materials your body uses to make focus, mood, and calming messengers.
| Compound | What It Does | Higher In | Category |
|---|---|---|---|
| ★Acetylcholine | The primary brain messenger for memory, learning, and muscle control, synthesized from choline and acetyl-CoA. | Lion's Mane | Neurotransmitter |
| ★Adrenaline | Epinephrine, the hormone and brain messenger that drives the fight-or-flight stress response. | Reishi | Neurotransmitter |
| ★Choline | An essential nutrient the body uses to make focus and memory messengers and to build healthy cell walls. | Reishi | Other |
| ★Glycerophosphocholine | A choline-rich nutrient that supports memory, clear thinking, and healthy brain cells. | Lion's Mane | Lipid |
| 1-Hexadecyl-2-acetyl-glycero-3-phosphocholine | Platelet-activating factor (PAF), a potent lipid mediator of inflammation and immune signaling. | Lion's Mane | Lipid |
| 1-Methylhistidine / 3-Methylhistidine | A histidine gene regulation product and sign of dietary meat intake and muscle protein turnover. | Reishi | Other |
| 1-Myristoyl-glycero-3-phosphocholine | A fatty nutrient that supplies choline for the brain's focus messengers and helps repair cell walls. | Reishi | Lipid |
| 1-Oleoyl-glycero-3-phosphocholine | A fatty nutrient that acts as a choline reserve the brain draws on to make its focus messengers. | Reishi | Lipid |
| 1-Palmitoyl-glycero-3-phosphocholine | A fatty nutrient in the blood that delivers choline the brain uses to make its focus messengers. | Lion's Mane | Endocannabinoid Lipid |
| 1-Stearoyl-glycero-3-phosphocholine | A fatty nutrient that helps keep cell walls balanced and carries choline to the brain. | Reishi | Lipid |
| 2-Methylcholine | A close cousin of choline that supports the brain's focus and memory signaling. | Reishi | Other |
| 6-Hydroxydopamine / Noradrenaline | A messenger the body makes from dopamine, studied for its role in focus and alertness. | Reishi | Neurotransmitter |
| Glutamic acid γ-methyl ester / O-Acetylhomoserine / 2-Aminoadipic acid | A glutamate derivative involved in the brain's activating signals and amino acid metabolism. | Reishi | Amino Acid |
| Isoglutamic acid | A form of the amino acid glutamate that helps balance the brain's activating signals and amino acid balance. | Lion's Mane | Amino Acid |
| N,N-Dimethylhistidine | A methylated histidine derivative involved in histamine metabolism and one-carbon cycling. | Reishi | Other |
| N-Acetylaspartylglutamic acid | A building block or messenger the body uses to make and balance brain brain messengers. | Reishi | Neurotransmitter |
| N-Acetylglutamic acid | A building block or messenger the body uses to make and balance brain brain messengers. | Reishi | Neurotransmitter |
| N-Acetylhistidine | A building block or messenger the body uses to make and balance brain brain messengers. | Reishi | Neurotransmitter |
| N-Acetyltyrosine ethyl ester | A building block or messenger the body uses to make and balance brain brain messengers. | Reishi | Neurotransmitter |
| N-Amidinoglutamic acid | A building block or messenger the body uses to make and balance brain brain messengers. | Reishi | Neurotransmitter |
| N-Carbamylglutamic acid | A building block or messenger the body uses to make and balance brain brain messengers. | Reishi | Neurotransmitter |
| N-Formylaspartic acid | A building block or messenger the body uses to make and balance brain brain messengers. | Lion's Mane | Neurotransmitter |
| N-Formylphenylalanine | A building block or messenger the body uses to make and balance brain brain messengers. | Reishi | Neurotransmitter |
| N-Lactoylphenylalanine | A building block or messenger the body uses to make and balance brain brain messengers. | Lion's Mane | Neurotransmitter |
| N-Methylglutamic acid | A building block or messenger the body uses to make and balance brain brain messengers. | Reishi | Neurotransmitter |
| N-Methyltyramine | A building block or messenger the body uses to make and balance brain brain messengers. | Reishi | Neurotransmitter |
| Octopamine / Dopamine | A building block or messenger the body uses to make and balance brain brain messengers. | Reishi | Neurotransmitter |
| Palmitoylcholine | A nutrient the brain uses to make acetylcholine, a messenger for focus and memory. | Reishi | Neurotransmitter |
| Phosphorylcholine | A nutrient the brain uses to make acetylcholine, a messenger for focus and memory. | Reishi | Neurotransmitter |
| Tyramine | A building block or messenger the body uses to make and balance brain brain messengers. | Reishi | Neurotransmitter |
| threo-3-Hydroxyaspartic acid | A building block or messenger the body uses to make and balance brain brain messengers. | Reishi | Neurotransmitter |
| threo-β-Methylaspartic acid | A building block or messenger the body uses to make and balance brain brain messengers. | Reishi | Neurotransmitter |
Gut-Brain Axis
★ 4 key27 compounds▾
The compounds your gut bacteria make that talk to your brain.
| Compound | What It Does | Higher In | Category |
|---|---|---|---|
| ★3,4-Dihydroxyphenylacetic acid | A major dopamine metabolite produced by gut bacteria, linking microbial activity to brain chemistry. | Lion's Mane | Other |
| ★5,6-Dihydroxyindole | A melanin building block from dopamine breakdown involved in pigment and cellular balance. | Reishi | Other |
| ★5-Hydroxyindoleacetic acid | The primary serotonin metabolite (5-HIAA), used as a marker of the body's serotonin production. | Lion's Mane | Other |
| ★Benzoic acid | A compound gut bacteria make from dietary polyphenols that supports the body’s natural detox. | Lion's Mane | Other |
| 2,3-Dihydroxybenzoic acid / 2,5-Dihydroxybenzoic acid | A microbial aromatic acid with iron-chelating properties and antioxidant activity in the gut. | Reishi | Other |
| 2,4-Dihydroxybenzoic acid | A phenolic compound produced by gut bacteria from dietary polyphenols with anti-inflammatory effects. | Lion's Mane | Other |
| 2,6-Dihydroxybenzoic acid | A plant acid with antimicrobial properties that helps balance gut microbiota composition. | Lion's Mane | Other |
| 3,5-Dihydroxybenzoic acid | A compound gut bacteria make from flavonoids with antioxidant and gut-supporting effects. | Lion's Mane | Other |
| 3-Hydroxyphenylacetic acid / p-Hydroxyphenylacetic acid | A tyrosine breakdown product produced by intestinal bacteria that reflects gut microbial metabolic activity. | Reishi | Other |
| 4-Hydroxyphenylacetaldehyde | A step the body makes while building its dopamine and adrenaline messengers. | Reishi | Other |
| 5-Hydroxy-2-indolecarboxylic acid-1 | A tryptophan metabolite involved in serotonin breakdown and gut immune signaling. | Reishi | Other |
| 5-Hydroxy-2-indolecarboxylic acid-2 | An indole derivative from microbial tryptophan metabolism with gut-brain signaling roles. | Reishi | Other |
| 5-Methoxyindoleacetic acid-1 | A melatonin metabolite reflecting pineal gland activity and indoleamine metabolism. | Lion's Mane | Other |
| 5-Methoxyindoleacetic acid-2 | An indoleacetic acid derivative from melatonin degradation involved in circadian regulation. | Lion's Mane | Other |
| Atrolactic acid / m-Ethoxybenzoic acid-2 / 3-Phenyllactic acid-2 / p-Methoxyphenylacetic acid-2 | A compound produced by gut microbiota from protein breakdown by gut bacteria. | Lion's Mane | Other |
| Indole-3-acetic acid | A gut-microbe metabolite from the indole family that supports the gut-brain connection. | Reishi | Gut-Brain |
| Indole-3-carboxaldehyde | A gut-microbe metabolite from the indole family that supports the gut-brain connection. | Lion's Mane | Gut-Brain |
| Indole-3-ethanol | A gut-microbe metabolite from the indole family that supports the gut-brain connection. | Reishi | Gut-Brain |
| Indole-3-glyoxylic acid | A gut-microbe metabolite from the indole family that supports the gut-brain connection. | Reishi | Gut-Brain |
| Indole-3-pyruvic acid | A gut-microbe metabolite from the indole family that supports the gut-brain connection. | Lion's Mane | Gut-Brain |
| Indoleacrylic acid | A gut-microbe metabolite from the indole family that supports the gut-brain connection. | Reishi | Gut-Brain |
| Testosterone acetate-1 | A processed form of a steroid hormone involved in energy and body composition. | Reishi | Gut-Brain |
| Testosterone acetate-2 | A processed form of a steroid hormone involved in energy and body composition. | Reishi | Gut-Brain |
| m-Hydroxybenzoic acid / p-Hydroxybenzoic acid | A gut-microbe-derived compound that takes part in gut-brain signaling. | Lion's Mane | Gut-Brain |
| o-Hydroxybenzoic acid | A gut-microbe-derived compound that takes part in gut-brain signaling. | Reishi | Gut-Brain |
| p-Aminobenzoic acid | A gut-microbe-derived compound that takes part in gut-brain signaling. | Reishi | Gut-Brain |
| p-Sulfobenzoic acid | A gut-microbe-derived compound that takes part in gut-brain signaling. | Reishi | Gut-Brain |
Nucleotide Metabolism
★ 4 key29 compounds▾
The building blocks your body uses to make and repair DNA and RNA.
| Compound | What It Does | Higher In | Category |
|---|---|---|---|
| ★5-Methylcytosine | A natural tag on DNA the body uses to quiet certain genes without changing the DNA itself. | Lion's Mane | Other |
| ★Adenine | A core building block the body uses to make and repair DNA, RNA, and cellular energy. | Reishi | Other |
| ★Cytidine | A natural building block the body uses to make healthy brain cells and cell walls. | Lion's Mane | Other |
| ★Cytosine | A core building block of DNA and RNA that also helps the body control which genes turn on. | Reishi | Other |
| 2'-Deoxycytidine | A DNA building block involved in recycling and essential for DNA replication and repair. | Lion's Mane | Other |
| 2'-Deoxyinosine | A building block DNA building block from adenosine deamination involved in building block recycling. | Reishi | Other |
| 2'-Deoxyuridine | A natural building block the body uses to make and repair DNA. | Reishi | Other |
| 2'-O-Methylcytidine | A modified building block that helps keep RNA stable and supports gene control. | Lion's Mane | Other |
| 2,4-Dihydroxypyrimidine-5-carboxylic acid | A building block breakdown product involved in uracil breakdown and nitrogen recycling. | Reishi | Other |
| 3-Methyladenine | A modified building block involved in DNA repair signaling and autophagy regulation in cells. | Lion's Mane | Other |
| 5-Methyl-2'-deoxycytidine | A tagged DNA building block the body uses to control which genes are active. | Reishi | Other |
| 5-Methylcytidine | A modified building block that helps the body control which genes turn on and keeps RNA stable. | Lion's Mane | Other |
| 7-Methylguanine | A modified building block that helps keep the body's genetic messages stable and readable. | Reishi | Other |
| Arabinosylhypoxanthine | A building block analog involved in building block metabolism and potential immune balance. | Reishi | Other |
| Argpyrimidine | An advanced glycation product of arginine and methylglyoxal, a marker of metabolic stress. | Reishi | Other |
| Guanine | A building block the body uses to make and repair DNA and RNA. | Reishi | Nucleotide |
| Guanosine | A building block the body uses to make and repair DNA and RNA. | Lion's Mane | Nucleotide |
| Hypoxanthine | A building block the body uses to make and repair DNA and RNA. | Reishi | Nucleotide |
| Inosine | A building block the body uses to make and repair DNA and RNA. | Reishi | Nucleotide |
| N1-Methylguanosine | A building block the body uses to make and repair DNA and RNA. | Lion's Mane | Nucleotide |
| N2,N2-Dimethylguanosine | A methyl-donor or gene regulation product the body uses to regulate genes and balance brain messengers. | Lion's Mane | Nucleotide |
| N2-Methylguanine | A building block the body uses to make and repair DNA and RNA. | Reishi | Nucleotide |
| N6-Methyladenine | A building block the body uses to make and repair DNA and RNA. | Reishi | Nucleotide |
| Tetrahydrouridine | A building block the body uses to make and repair DNA and RNA. | Reishi | Nucleotide |
| Thymidine | A building block the body uses to make and repair DNA and RNA. | Lion's Mane | Nucleotide |
| Thymine | A building block the body uses to make and repair DNA and RNA. | Reishi | Nucleotide |
| Uracil | A building block the body uses to make and repair DNA and RNA. | Reishi | Nucleotide |
| Uridine | A building block the body uses to make and repair DNA and RNA. | Lion's Mane | Nucleotide |
| Xanthine | A building block the body uses to make and repair DNA and RNA. | Reishi | Nucleotide |
Steroid & Hormone Metabolism
★ 3 key27 compounds▾
The hormones and their building blocks that shape stress, mood, and balance.
| Compound | What It Does | Higher In | Category |
|---|---|---|---|
| ★Aldosterone | A hormone that helps the body manage salt, water, and blood pressure. | Lion's Mane | Other |
| ★Cortisone | An inactive form of the stress hormone cortisol that the body switches on in tissues to help control inflammation. | Lion's Mane | Other |
| ★Dehydroisoandrosterone 3-sulfate-1 | DHEA-S, the most abundant circulating steroid that serves as a building block for sex hormones and has neuroprotective effects. | Reishi | Other |
| 11α-Hydroxyprogesterone / 11β-Hydroxyprogesterone | A hydroxylated progesterone metabolite involved in adrenal steroid production pathways. | Reishi | Other |
| 11β-Hydroxyandrost-4-ene-3,17-dione | An adrenal androgen metabolite involved in cortisol and sex hormone production. | Lion's Mane | Other |
| 17α-Hydroxyprogesterone | A steroid hormone building block essential for cortisol and sex hormone production. | Reishi | Other |
| 18-Hydroxycorticosterone | A building block the body uses to make hormones that help regulate blood pressure. | Reishi | Other |
| 19-Hydroxyandrostenedione | A raw material the body uses when making estrogen. | Reishi | Other |
| 19-Hydroxytestosterone | A step the body uses when converting testosterone into estrogen. | Lion's Mane | Other |
| 2-Hydroxyestradiol | A catechol estrogen with antioxidant properties involved in estrogen metabolism and detoxification. | Reishi | Other |
| 20α-Hydroxyprogesterone | A progesterone metabolite reflecting progesterone clearance and luteal phase activity. | Lion's Mane | Other |
| 21-Deoxycortisol-1 | A cortisol building block that accumulates in certain adrenal enzyme deficiencies. | Lion's Mane | Other |
| 21-Deoxycortisol-2 / Corticosterone / Cortexolone | A step the body uses to make its stress hormones from cholesterol. | Reishi | Other |
| 4-Androstene-3,17-dione | Androstenedione, a key androgen building block converted to testosterone and estrogen in target tissues. | Reishi | Other |
| 5β-Tetrahydrocortisol | A major cortisol metabolite reflecting HPA axis activity and stress hormone clearance. | Reishi | Other |
| Dehydroisoandrosterone 3-sulfate-2 | A steroid hormone or building block involved in the body's stress, energy, and hormonal balance. | Reishi | Steroid |
| Dehydroisoandrosterone 3-sulfate-3 | A steroid hormone or building block involved in the body's stress, energy, and hormonal balance. | Reishi | Steroid |
| Deoxycorticosterone | A building block the body uses to make and repair DNA and RNA. | Lion's Mane | Steroid |
| Ethynyl estradiol-1 | A steroid hormone or building block involved in the body's stress, energy, and hormonal balance. | Reishi | Steroid |
| Ethynyl estradiol-2 | A steroid hormone or building block involved in the body's stress, energy, and hormonal balance. | Reishi | Steroid |
| Hydroxyprogesterone caproate | A steroid hormone form involved in the body's hormonal signaling. | Reishi | Steroid |
| Medroxyprogesterone | A steroid hormone form involved in the body's hormonal signaling. | Reishi | Steroid |
| Methoxyestradiol | A steroid hormone or building block involved in the body's stress, energy, and hormonal balance. | Reishi | Steroid |
| Pregnenolone sulfate | A steroid hormone or building block involved in the body's stress, energy, and hormonal balance. | Reishi | Steroid |
| Progesterone-1 | A steroid hormone form involved in the body's hormonal signaling. | Reishi | Steroid |
| Progesterone-2 | A steroid hormone form involved in the body's hormonal signaling. | Reishi | Steroid |
| Testosterone | A processed form of a steroid hormone involved in energy and body composition. | Reishi | Steroid |
Polyphenols & Flavonoids
★ 7 key24 compounds▾
Plant antioxidants that help protect your cells from everyday wear.
| Compound | What It Does | Higher In | Category |
|---|---|---|---|
| ★Bisdemethoxycurcumin | The most potent curcuminoid for anti-inflammatory activity, inhibiting NF-κB and COX-2 pathways. | Lion's Mane | Other |
| ★Catechin gallate | A polyphenol ester with potent antioxidant activity that supports cardiovascular and brain health. | Lion's Mane | Other |
| ★Curcumin | The primary bioactive in turmeric with powerful anti-inflammatory, antioxidant, and neuroprotective properties. | Reishi | Other |
| ★Daidzein-1 | A natural soy compound that supports bone and heart health. | Lion's Mane | Other |
| ★Daidzein-2 | A plant compound metabolized by gut bacteria into equol, with enhanced estrogenic and antioxidant effects. | Lion's Mane | Other |
| ★Epicatechin-1 | A flavan-3-ol found in green tea and cocoa, studied in vascular and cognitive research. | Lion's Mane | Other |
| ★Epicatechin-2 | A plant antioxidant with heart-supporting effects and support for healthy blood flow. | Lion's Mane | Other |
| 3',4',5,7-Tetramethoxyflavone-1 | A polymethoxylated flavone with enhanced bioavailability and anti-inflammatory activity. | Reishi | Other |
| 3',4',5,7-Tetramethoxyflavone-2 | A plant antioxidant with antioxidant and potential neuroprotective properties. | Reishi | Other |
| 3,5,7,4'-Tetramethoxyflavone | A fully methylated flavone studied for its membrane permeability and antioxidant properties. | Lion's Mane | Other |
| 3,5,7-Trimethoxyflavone-1 | A trimethoxylated flavone with antioxidant properties and enhanced cellular uptake. | Reishi | Other |
| 3,5,7-Trimethoxyflavone-2 | A plant antioxidant studied for anti-inflammatory and protective effects. | Reishi | Other |
| 5,7-Dimethoxyflavone-1 | A chrysin derivative with improved bioavailability that helps balance the brain’s calming signals for anxiolytic effects. | Lion's Mane | Other |
| 5,7-Dimethoxyflavone-2 | A methoxylated chrysin analog with enhanced blood-brain barrier penetration and neuroprotective activity. | Lion's Mane | Other |
| Datiscetin / Kaempferol | A flavonol related to kaempferol with antioxidant activity and potential anti-allergic properties. | Lion's Mane | Other |
| Epigallocatechin gallate | The signature green-tea catechin (EGCG), studied for strong antioxidant activity. | Lion's Mane | Polyphenols |
| Epigallocatechin-1 | A plant polyphenol studied for its antioxidant activity. | Reishi | Polyphenols |
| Epigallocatechin-2 | A plant polyphenol studied for its antioxidant activity. | Lion's Mane | Polyphenols |
| Gallocatechin | A plant polyphenol studied for its antioxidant activity. | Lion's Mane | Polyphenols |
| Genistein-1 | A plant polyphenol studied for its antioxidant activity. | Lion's Mane | Polyphenols |
| Genistein-2 | A plant polyphenol studied for its antioxidant activity. | Reishi | Polyphenols |
| Quercetin | A plant flavonoid studied for its antioxidant and calming, anti-inflammatory support. | Reishi | Polyphenols |
| Quercetin 3-rutinoside | A plant flavonoid studied for its antioxidant and calming, anti-inflammatory support. | Lion's Mane | Polyphenols |
| Resveratrol | A plant polyphenol found in grapes, studied for antioxidant support and healthy aging. | Reishi | Polyphenols |
Energy & Mitochondrial Function
★ 6 key22 compounds▾
The compounds your cells use to turn food into usable energy.
| Compound | What It Does | Higher In | Category |
|---|---|---|---|
| ★ADP | Adenosine diphosphate, the raw material for the cell’s energy-making machinery that drives energy production in the cell's power centers. | Reishi | Energy |
| ★AMP | Adenosine monophosphate, an energy sensor that helps regulate the body’s metabolism and the making of new cell energy centers. | Lion's Mane | Energy |
| ★Campesterol | A plant sterol involved in membrane structure, studied in relation to cholesterol absorption. | Reishi | Energy Lipid |
| ★Citric acid | The first step in the body's energy cycle, helping cells turn food into usable energy. | Reishi | Energy |
| ★Coenzyme Q10 | An essential electron carrier in the the cell's energy centers that generates cellular ATP. | Lion's Mane | Other |
| ★Fumaric acid | A step in the body's energy (citric acid) cycle, involved in cellular energy production. | Lion's Mane | Other |
| 2-Oxoglutaric acid | A central hub in how cells make energy and use protein building blocks. | Lion's Mane | Amino Acid |
| 3',5'-ADP | A small fragment the body recycles to help keep its cellular energy supply running. | Reishi | Energy |
| 3'-AMP | A building block the body recycles to help renew its cellular energy supply. | Lion's Mane | Energy |
| Adenylosuccinic acid | A building block production step linking IMP to AMP production for energy molecule generation. | Reishi | Other |
| Benzylsuccinic acid | A microbial toluene breakdown product used as a sign of anaerobic aromatic compound metabolism. | Lion's Mane | Other |
| Deamido-NAD+ | A building block the body uses to make a key cellular energy helper that powers the mitochondria. | Lion's Mane | Energy |
| Fumaric acid monomethyl ester | A fumarate derivative with immunomodulatory effects that activates the Nrf2 antioxidant pathway. | Lion's Mane | Other |
| Guanidinosuccinic acid | An uremic toxin and arginine metabolite that reflects kidney function and nitrogen metabolism. | Reishi | Other |
| Homocitric acid | A citric acid homolog involved in lysine production in fungi and cellular energy cycle-related metabolism. | Reishi | Energy |
| Isocitric acid | A step in the body's energy cycle the body uses to generate cellular energy. | Reishi | Energy |
| N2-Succinylornithine | An organic-acid step the body uses in its energy and amino-acid metabolism. | Reishi | Energy |
| Nα-Succinylarginine | An organic-acid step the body uses in its energy and amino-acid metabolism. | Reishi | Energy |
| Succinic acid | A step in the body's energy cycle the body uses to generate cellular energy. | Reishi | Energy |
| Succinic semialdehyde | An organic-acid step the body uses in its energy and amino-acid metabolism. | Lion's Mane | Energy |
| Succinylacetone | An organic-acid step the body uses in its energy and amino-acid metabolism. | Lion's Mane | Energy |
| cAMP | A building block the body uses to store and transfer cellular energy. | Reishi | Energy |
Vitamins & Cofactors
★ 8 key14 compounds▾
The essential vitamins and helper molecules your body needs to function.
| Compound | What It Does | Higher In | Category |
|---|---|---|---|
| ★1-Methylnicotinamide | A metabolite of niacin (vitamin B3), studied in vascular and anti-inflammatory research. | Lion's Mane | Other |
| ★4-Pyridoxic acid | The form the body clears from vitamin B6, used as a sign of B6 status and metabolism. | Reishi | Vitamin |
| ★Dethiobiotin | A step the body uses to make biotin (vitamin B7), essential for carboxylase enzymes. | Lion's Mane | Vitamin |
| ★Ergocalciferol-2 | Vitamin D2, produced by UV irradiation of ergosterol in mushrooms; supports calcium absorption and immune function. | Reishi | Vitamin |
| ★Nicotinic acid | Niacin (vitamin B3), which the body needs to make cellular energy and support healthy fats. | Reishi | Other |
| ★Pyridoxal | An active form of vitamin B6 that the body relies on for over 140 everyday reactions. | Lion's Mane | Vitamin |
| ★Pyridoxine | Vitamin B6, which the body needs to make calming and mood messengers like serotonin, dopamine, and GABA. | Lion's Mane | Vitamin |
| ★Riboflavin | Vitamin B2, which the body uses to make the helper molecules (cofactors) that power cell energy reactions. | Reishi | Vitamin |
| 6-Hydroxynicotinic acid | A niacin breakdown product from vitamin B3 metabolism via the kynurenine pathway. | Reishi | Other |
| Isonicotinamide / Nicotinamide | A form of vitamin B3 the body uses to make cellular energy and support healthy aging. | Lion's Mane | Other |
| Isonicotinic acid | A relative of niacin (vitamin B3) involved in the body's energy production. | Reishi | Other |
| N-Methylnicotinamide | A methylated niacin metabolite that reflects vitamin B3 status and gene regulation capacity. | Reishi | Other |
| Retinol-1 | Vitamin A, critical for vision, immune function, gene expression, and cellular differentiation. | Reishi | Other |
| Retinol-2 | A form of vitamin An involved in vitamin A signaling, skin health, and healthy skin and tissue. | Reishi | Other |
Antioxidant & Redox Balance
★ 8 key11 compounds▾
Compounds that protect your cells from damage and keep them in balance.
| Compound | What It Does | Higher In | Category |
|---|---|---|---|
| ★Ascorbic acid | Vitamin C, a powerful antioxidant that supports healthy skin, collagen, and immune defense. | Reishi | Vitamin Antioxidant |
| ★Hippuric acid | A benzoate-glycine processed form reflecting gut microbial activity and hepatic detoxification capacity. | Reishi | Other |
| ★Lauric acid | A medium-chain fatty acid with antimicrobial properties that supports immune function and gut health. | Reishi | Other |
| ★Ophthalmic acid | An antioxidant-related compound used as a biomarker for cell stress and low antioxidant levels in the liver. | Reishi | Other |
| ★α-Tocopherol | The most biologically active form of vitamin E, an antioxidant involved in protecting cell membranes. | Lion's Mane | Vitamin Antioxidant |
| ★α-Tocopherol acetate | A stabilized vitamin E ester that is hydrolyzed in the body to release active α-tocopherol. | Lion's Mane | Vitamin Antioxidant |
| ★γ-Tocopherol-1 | A vitamin E form with unique anti-inflammatory properties via trapping reactive nitrogen species. | Lion's Mane | Vitamin Antioxidant |
| ★γ-Tocopherol-2 | A form of vitamin E that complements α-tocopherol in neutralizing harmful free radicals. | Reishi | Vitamin Antioxidant |
| 4-Hydroxyhippuric acid | A phase II detoxification product from gut microbial metabolism of dietary polyphenols. | Reishi | Other |
| Ascorbate 2-phosphate | A stable phosphorylated form of vitamin C that serves as an intracellular antioxidant reservoir. | Reishi | Vitamin Antioxidant |
| Cyanuric acid | A triazine compound involved in nitrogen metabolism with potential applications in urea cycle studies. | Lion's Mane | Other |
Endocannabinoid System
★ 4 key14 compounds▾
Your body's natural calm-and-balance compounds.
| Compound | What It Does | Higher In | Category |
|---|---|---|---|
| ★N-Oleoylserine | A lipid amide that helps balance bone formation, vascular tone, and endocannabinoid-like signaling. | Reishi | Other |
| ★Oleoyl ethanolamide | An endocannabinoid-like lipid involved in appetite and energy-balance signaling through PPAR-alpha. | Reishi | Endocannabinoid |
| ★Anandamide | An endocannabinoid the body makes naturally, sometimes called the bliss molecule, that acts on the CB1 and CB2 receptors of the endocannabinoid system. | Reishi | Endocannabinoid |
| ★Palmitoylethanolamide | A natural fatty acid amide in the endocannabinoid family, studied in inflammation and nerve-signaling research. | Reishi | Endocannabinoid |
| AEA(18:3)-1 | An anandamide-type endocannabinoid built on linolenic acid, part of the body's endocannabinoid system. | Reishi | Endocannabinoid |
| AEA(18:3)-2 | An anandamide-type endocannabinoid involved in the body's endocannabinoid signaling. | Reishi | Endocannabinoid |
| AEA(20:3) | A natural calming fat that helps balance the body's relaxation and comfort signals. | Reishi | Endocannabinoid |
| AEA(20:5) | A natural calming fat with soothing, anti-inflammatory effects. | Reishi | Endocannabinoid |
| AEA(22:4) | A natural calming fat involved in the body's relaxation and balance signals. | Reishi | Endocannabinoid |
| AEA(22:6)-1 | A DHA-derived endocannabinoid (synaptamide) studied in neurodevelopment research. | Lion's Mane | Endocannabinoid |
| AEA(22:6)-2 | A natural calming fat with neuroprotective and brain-calming effects. | Reishi | Endocannabinoid |
| Stearoyl ethanolamide | A fatty acid amide in the endocannabinoid family, involved in inflammation and nerve signaling. | Reishi | Endocannabinoid |
| Linoleyl ethanolamide | An endocannabinoid-like fatty acid amide involved in the body's pain and inflammation signaling. | Reishi | Endocannabinoid |
| N-Oleoylglycine | A fatty acid amide studied in relation to the endocannabinoid system. | Reishi | Endocannabinoid |
Carbohydrate Metabolism
★ 2 key2 compounds▾
The sugars and related compounds your body uses for energy.
| Compound | What It Does | Higher In | Category |
|---|---|---|---|
| ★Sucrose 6'-phosphate | A phosphorylated sugar step in sucrose production and carbohydrate energy storage. | Reishi | Other |
| ★Trehalose 6-phosphate | A sugar phosphate that signals carbon availability and protects proteins during cellular stress. | Lion's Mane | Other |
Other Metabolic Pathways
15 compounds▾
Additional metabolites we mapped that don't fall into one specific group.
| Compound | What It Does | Higher In | Category |
|---|
| 1,3-Diaminopropane | A polyamine building block involved in cell growth, gene expression, and spermidine production. | Reishi | Other |
| 1-Aminocyclopropane-1-carboxylic acid | The direct used by the body to make the plant hormone ethylene, also found in fungi with signaling roles. | Lion's Mane | Other |
| 1-Deoxynojirimycin | A natural glucose analog that inhibits alpha-glucosidase, reducing carbohydrate absorption. | Reishi | Other |
| 1-Deoxysphinganine | An atypical fatty building block linked to metabolic syndrome and sensory neuropathy when elevated. | Reishi | Other |
| 10-Hydroxydecanoic acid | A hydroxylated medium-chain fatty acid with antimicrobial and anti-inflammatory properties. | Lion's Mane | Other |
| 10-Hydroxyoctadecanoic acid-1 | A hydroxylated stearic acid involved in lipid signaling and skin barrier function. | Reishi | Other |
| 10-Hydroxyoctadecanoic acid-2 | A fatty acid with potential roles in inflammatory balance and lipid metabolism. | Reishi | Other |
| 16-Epiestriol | A form of the hormone estriol involved in estrogen metabolism and hormonal balance. | Reishi | Other |
| 16-Hydroxyhexadecanoic acid-1 | A hydroxylated palmitic acid involved in cutin production and lipid barrier formation. | Reishi | Other |
| 16-Hydroxyhexadecanoic acid-2 | A fatty acid the body uses to build its protective outer layers. | Reishi | Other |
| 16α-Hydroxyestrone | An estrogen metabolite associated with estrogenic activity and hormone detoxification pathways. | Reishi | Other |
| 1H-Imidazole-4-propionic acid | A histamine-related imidazole compound involved in histidine breakdown and immune signaling. | Reishi | Other |
| 2,6-Diaminopimelic acid | A lysine production step unique to bacteria and fungi, involved in cell wall construction. | Lion's Mane | Other |
| 2-Aminoisobutyric acid / 2-Aminobutyric acid | A non-proteinogenic amino acid involved in protein stability, used as a thyroid function marker. | Reishi | Other |
| 2-Carboxybenzaldehyde | A step in the body’s processing of certain compounds and clearing outside substances. | Lion's Mane | Other |